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【教师科研快讯】张富仁老师在《Green Chemistry》杂志上发表科研成果
2019-05-31 16:16  

    20195月,我院教师张富仁博士在化学领域重要期刊《Green Chemistry》(2019年影响因子IF9.405

在线发表题为A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-ones using a solid acid as a recyclable catalyst的学术成果(文章链接:https://pubs.rsc.org/en/content/articlelanding/2019/gc/ c9gc01120j#!divAbstract

Abstract

A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-one derivatives has been described. The reactions can be readily performed by mixing inexpensive starting materials using two-step methods under mild conditions, and the products can be easily obtained from the mother liquid without any further treatment. Moreover, the solid acid catalyst can be circulated at least 6 times without obvious deactivation. Furthermore, a mechanism for the reaction process has been proposed. Overall the bond forming efficiency, the use of green solvent as the reaction medium, recyclability of the solid acid catalyst, easy work-up/purification, and a wide substrate scope make this method highly attractive to assemble heterocyclic scaffolds.

自从参加工作以来,张富仁老师在具有高生理活性和药物活性杂环化合物的合成领域进行了相关的研究工作,并取得了一系列的研究成果,到目前为止,共发表SCI收录研究论文二十余篇。目前,张富仁老师是Journal of Organic Chemistry, New Journal of chemistry, ChemistrySelect, Journal of Heterocyclic Chemistry, Organic Preparations and Procedures International, Polycyclic Aromatic Compounds Letter in Organic Chemistry等国际学术杂志的审稿人。

供稿:材料化学与工程系

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