余乐茂 博士，1989年出生，毕业于中山大学药学院。2018年7月进入绍兴文理学院化学与化工学院药学系工作。主要研究领域为有机化学、药物合成化学、手性不对称催化等。至今以第一作者在Chem.Commun., Eur. J. Med. Chem., Org. Chem. Front.等杂志发表SCI论文4篇，累计影响因子IF > 20.
Tel: 13450287832
Email: yulm@usx.edu.cn; 13450287832@163.com
研究方向
a)具有潜在药物活性的吲哚类衍生物的设计与合成
b)偶极子参与的环加成反应研究
c)不对称方法学研究
教育经历
2008.09 - 2012.06 江西中医药大学， 学士
2012.09 - 2015.06 中山大学，硕士
2015.09 - 2018.06 中山大学，博士，导师：蒋先兴 教授，王锐 院士
2018.07 - 至今 绍兴文理学院化学化工学院，讲师
教学情况
药用植物学和生药学
新药研究与开发
论著专利：
1)Le-Mao Yu, Yuan Zhong, Jicong Yu, Lu Gan, Zhengjun Cai, Rui Wang* and Xianxing Jiang*. Highly Diastereoselective Oxa-[3+3] Cyclization with C,N-Cyclic Azomethine Imines via Copper-Catalyzed Aerobic Oxygenated C=C Bond of Indoles. Chem. Commun. 2018, 54, 2353-2356. （IF=6.32）
2)Le-Mao Yu, Xiao-Ru Zhang , Xiao-Bing Li , Yuan Yang , Hong-Yu Wei , Xi-Xin He , Lian-Quan Gu, Zhi-Shu Huang, Yves Pommier, Lin-Kun An*. Synthesis and biological evaluation of 6-substituted indolizinoquinolinediones as catalytic DNA topoisomerase I inhibitors. Eur. J. Med. Chem. 101 (2015) 525 - 533. （IF=4.52）
3)Le-Mao Yu,?,? Zhu Hu,?,? Yu Chen,? Sophia Lopez, Azhar Ravji, Evgeny Kiselev, Christophe Marchand, Yves Pommier, Lin-Kun An*,?. Synthesis and Structure-Activity Relationship of Furoquinolinediones as Selective Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2). Eur. J. Med. Chem. 151 (2018) 777 -796.（IF=4.52）
4)Ji-cong Yu,? Le-Mao Yu,? Xiao-yun Zhao, Lu Gan, Zeng-chen Wang, Rui Wang* and Xianxiang Jiang*. Organocatalytic Asymmetric [3+2] Cycloaddition of 1,4-Dithiane -2,5-diol with Alzactones: Access to Chiral Dihydrothiophen-2(3H)-one Derivatives. Org. Chem. Front. 2018, 5, 2040-2044（IF=4.95）
5)Hui Yang,? Haowen Wang,? Tengwei Zhu,? Le-Mao Yu, Jianwen Chen, Luxia Wang, Lei Shi, Ding Li, Lian-Quan Gu , Zhi-Shu Huang , Lin-Kun An*. Syntheses and antibacterial activity of soluble 9-bromo substituted indolizinoquinoline-5,12-dione derivatives. Eur. J. Med. Chem. 127 (2017) 166 -173. （IF=4.52）
6)Qian Yu;? Hui Yang;? Teng-Wei Zhu; Le-Mao Yu; Jian-Wen Chen; Lian-Quan Gu; Zhi-Shu Huang., Lin-Kun An*. Synthesis, Cytotoxicity and Structure-Activity Relationship of Indolizinoquinolinedione Derivatives as DNA Topoisomerase IB Catalytic Inhibitors. Eur. J. Med. Chem. 152 (2018) 195 -207.（IF=4.52）