【姓名】李琰
【职称】讲师
【职务】无
【联系方式】
【电子邮箱】liyan@usx.edu.cn
【个人简介】
2014.7-至今 绍兴文理学院,化学化工学院,讲师,硕士生导师
2009.9-2014.6 兰州大学,化学化工学院,博士(导师:周波教授)
2005.9-2009.6 兰州大学,化学化工学院,学士
【研究方向】
1)有机化学
2)药物化学
【科研项目】
1. 2018-2021,主持国家自然科学基金(31800292),在研
2.2015-2018,主持浙江省自然科学基金(LQ16C050001),结题
【研究成果】
【发表论文】
1. An effective strategy to develop active cinnamic acid-directed antioxidants based on elongating the conjugated chains, Food Chemistry, 2014, 158: 41-47;
2. Insights into the importance for designing curcumin-inspired anticancer agents by a prooxidant strategy: The case of diarylpentanoids, Free Radical Biology & Medicine, 2015, 85: 127-137;
3. Hexamethoxylated monocarbonyl analogues of curcumin cause G2/M cell cycle arrest in NCI-H460 cells via Michael acceptor-dependent redox intervention, Journal of Agricultural and Food Chemistry, 2015, 63(35): 7731-7742;
4. Effects of the π-electrons in fused polycyclic aromatic hydrocarbons on positron annihilation, Radiation Physics and Chemistry, 2019, 163 (3): 39-44;
5. A novel quinazoline-based analog induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells via a ROS-dependent mechanism, Biochemical and Biophysical Research Communications , 2017, 486: 314-320.