【姓名】朱柯武

【职称】教授

【联系方式】

【电子邮箱】kwzhu00@hotmail.com 

【个人简介】

2020.7-至今 绍兴文理学院，医学院，教授，硕士生导师 

2015.7-2020.4 成都倍特药业股份有限公司，首席科学家 

2012.10-2015.7 新加坡科技研究局/葛兰素史克药物研发实验室，Team Leader

2009.2-2012.10 3M（新加坡） 药物递送系统事业部，Principle Formulation Chemist

2003.8-2009.2 新加坡科技研究局化工研究院，Senior Research Fellow 2002.8-2003.8 新加坡-麻省理工学院学术联盟，博士后研究员

1999.4-2002.8 新加坡国立大学，化工系，博士研究生（导师：Chi-Hwa Wang 教授）

1995.9-1998.2 浙江大学，化工学院，硕士

1989.9-1993.7 西安交通大学，化工系，学士

【研究方向】  

1） 药物递送系统

2） 新型药物制剂

3） 粉体技术 

【科研项目】

1. 2006-2008 ， Dispersion of powder aggregates in air flow field ( 主 持 , ICES/06-422001,已结题) 

2. 2005-2007，Influence of moisture sorption on the electrostatic charge and the performance of drug delivery through a dry powder inhaler ( 主持ICES/05-422001, 已结题) 

3. 2005-2008, Fabrication of large hollow nanoaggregates carrier for inhalation drug delivery (共同主持, ICES/05-122001, 已结题)  

4. 2010-2012，Development of a novel blending apparatus and process for the formulation development of dry powder inhaler drug delivery (PI, 3M Discovery Grant，已结题)  

 

【研究成果】

【发表论文】

1.        S. Madhusudana Rao, Kewu Zhu, Chi-Hwa Wang, Sankaran Sundaresan, (2001) Electrical

Capacitance Tomography measurements on the pneumatic conveying of solids, Ind. Eng. Chem. Res., 40, 4216-4226.  

2.         Kewu Zhu, S. Madhusudana Rao, Chi-Hwa Wang, Sankaran Sundaresan, (2003）Electrical Capacitance Tomography measurements on the vertical and Inclined pneumatic conveying of granular solids, Chem. Engi.Sci., 58, 4225-4245. (most cited paper from 2003-2006).

3.        Kewu        Zhu, S. Madhusudana Rao, Qiau He Huang, Chi-Hwa Wang, Shuji Matsusaka, Hiroaki

Masuda, (2004). On the electrostatics of pneumatic conveying of granular materials using electrical capacitance tomography, Chem. Engi. Sci., 59, 3201-3213.

4.         Kewu Zhu, Chun Kit Wong, S. Madhusudana Rao, Chi-Hwa Wang, (2004). Pneumatic conveying of granular solids in horizontal and inclined pipes, AIChE J., 50, 1729-1745.

5. Fengxi Chen, Kewu Zhu, Lin Huang, Yuxiang Chen, Fethi Kooli, (2006). Preparation of rodlike t-ZrO2 nanoparticles by two-step calcination of 1,12-diaminododecane-zirconia mesostructured composites. Mater. Res. Bull., 41, 10-18.

6. Shoucang Shen, Fengxi Chen, Ann Pui Shan Chow, Phanapavudhikul Ponpan, Kewu Zhu, Reginald B.H. Tan, (2006). Synthesis of SBA-15 mesoporous silica via dry-gel conversion route. Micropor. Mesopor. Mater.. 92, 300-308.

7. Kewu Zhu, Reginald B.H. Tan, Fengxi Chen, Kunn Hadinoto Ong, Paul W.S. Heng (2007). Influence of particle wall adhesion on particle electrification in mixers. Int. J. Pharm., 328, 22-34.

8. Fengxi Chen, Kewu Zhu, Geok Joo Gan, Shoucang Shen, Fethi Kooli, (2007). Hydrothermal processing of amorphous hydrous zirconia gels in the presence of 1,12-diaminododecane. Mater. Res. Bull., 42, 1128-1136.

9. Kunn Hadinoto Ong, Kewu Zhu, Reginald B.H. Tan, (2007). Drug release study of large hollow nanoparticulate aggregates carrier particles for pulmonary delivery. Int. J. Pharm., 341, 195-206.

10. Kewu Zhu, Reginald B.H. Tan, Wai Kiong Ng, Shoucang Shen, Qi Zhou, Paul W.S. Heng, (2008). Analysis of the influence of relative humidity on the moisture sorption of particles and the aerosolisation process in a dry powder inhaler. J. Aerosol Sci., 39, 510-524.

11. Shoucang Shen, Pui Shan Chow, Sanggu Kim, Kewu Zhu, Reginald B.H. Tan, (2008). Synthesis of carboxyl-modified rod-like SBA-15 by rapid co-condensation. J. Colloid. Interf. Sci., 321, 365-372.

12. Kewu Zhu, Wai Kiong Ng, Shoucang Shen, Reginald B.H. Tan, Paul W.S. Heng. (2008).

Design of a device for simultaneous particle size and electrostatic charge measurement of inhalation drugs. Pharm. Res., 25(11),2488-2496.  

13. Keat Theng Chow, Kewu Zhu, Reginald B.H. Tan, Paul W.S. Heng, (2008). Investigation of electrostatic behavior of a lactose carrier for dry powder inhalers. Pharm. Res., 25（12）, 2822-2834.

 

【讲座报告】

1. S.M. Rao, Kewu Zhu, S. Sundaresan, C.H. Wang, (1999). ECT measurements on the

pneumatic conveying of granular materials. AIChE Annual Meeting, Dallas, Texas, USA.

2. S.M. Rao, Kewu Zhu, C.H. Wang, S. Sundaresan, (2000). Electrical capacitance tomography measurements on the pneumatic conveying of solids: effect of pipe bend", AIChE Annual Meeting, Los Angeles, USA.

3. Kewu Zhu, S. M. Rao, C. H. Wang, (2001). CFD studies on the dilute-phase horizontal pneumatic conveying of granular materials. Symposium on Transport Phenomena and its Applications, Taipei, Proceedings, 161-164.

4. Kewu Zhu, S. Madhusudana Rao, Chi-Hwa Wang, (2001). Pressure and particle concentration measurements on the pneumatic conveying of granular materials.  6th World Chemical Engineering Conference, Melbourne, Australia.

5. S.M. Rao, Kewu Zhu, C.H. Wang, S. Sundaresan, (2001). ECT measurements on vertical and inclined pipes for the pneumatic conveying of granular solids. AIChE Annual Meeting, Nova, USA.

6. Kewu Zhu, S.M. Rao, C.H. Wang, S. Sundaresan, (2002). Numerical study on the formation of cluster in a horizontal gas-solid flow. Asia Pacific Conference of Chemical Engineering. Christchurch, New Zealand.

7. Kewu Zhu, Jun Yao, C.H.Wang, (2004). On the Electrostatics of Pneumatic Conveying of granular materials. MIT’s online institutional repository. 

8. Kewu Zhu, Kwek Jin Wang, Reginald BH Tan, (2004). CFD study on aerosol deposition in human upper respiratory tract. AIChE Annual Meeting, Austin, Texas.

9. Kewu Zhu, Kwek Jin Wang, Reginald B.H. Tan, Ann Pui San Chow, (2005). Influence of

moisture on particle flow properties. 7th World Congress of Chemical Engineering, Glasgow, Scotland.  

10. Kewu Zhu, Xiaohong Wei, Reginald B.H. Tan, Paul W.S. Heng, (2006). Investigation of particle electrification in mixers – effect of particle size, mixer type, rotation speed. AIChE Annual Conference, Sanfrancisco.

11. Kunn Hadinoto-Ong, Kewu Zhu, Reginald B.H. Tan, (2006). Dry powder serosol delivery of large hollow nanoparticle aggregates as prospective carriers of nanoparticulate drugs:  effects of phospholipids  concentration.  17th  drug delivery to the lungs conference European Aerosol Society, Edinburgh, Scotland.

12. Shoucang Shen, Fengxi Chen, Ann Pui Shan Chow, Ponpan Phanapavudhikul, Kewu Zhu, Reginald B.H. Tan, (2006). Modified mesoporous SBA-15 submicron particles as functional excipients for effective oral drug delivery. 2nd international congress of on Nanobiotechnology in Europe, the "NanoBio-Europe '06", 14-16 June 2006, Grenoble, France.

13. Kewu Zhu, Adeline Y.Ch. Wong, Syuk Yee Liow, Reginald B.H. Tan, (2007). Influence of relative humidity on the performance of drug delivery through a dry powder inhaler. Proceeding of Asian Pacific Particle Technology Forum, Beijing.

14. Kewu Zhu, Wai Kiong Ng, Reginald B.H. Tan, (2008). On the role of electrostatic charge on the drug delivery through a dry powder inhaler. AIChE Annual Meeting, Philadelphia, USA.